CASMI

Publications

Academic Papers

Naughton, B., Roberts, L., Dopson, S., Chapman, S., and Brindley, D. (in press). The Effectiveness of Medicine Authentication Technology to Detect Counterfeit, Recalled and Expired Medicines: A Two Stage Quantitative Secondary Care Study. BMJ Open, 6. Available here.

Faulkner, S. D. (2017) Early access to innovation – how much can we achieve? The New Statesman, January 27 – February 2, Suppl., 22-23. Available here.

Diez-Perez, A., Naylor K.E., Abrahamsen, B., Agnusdei, D., Brandi, M.L., Cooper. C., Dennison, E., Eriksen, E.F., Gold, D.T., Guañabens, N., Hadji, P., Hiligsmann, M., Horne, R., Josse, R., Kanis, J.A., Obermayer-Pietsch, B., Prieto-Alhambra, D., Reginster, J.E., Rizzoli, R., Silverman, S., Carola Zillikens, M., and Eastell, R. (2017). International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates. Osteoporosis International, 1-8. DOI: 10.1007/s00198-017- 3906-6

Heller, M., Chapman, S.C.E. and Horne, R. (2017) No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects. Psychology & Health, 32(4). Doi: 10.1080/08870446.2016.1273355

Montgomery, J. (2017). Data sharing and the idea of ownership. The New Bioethics: A Multidisciplinary Journal of Biotechnology and the Body. 23(1), 81-86.

Morrell, L., Wordsworth, S., Rees, S., and Barker, R. (2017). Does the Public Prefer Health Gain for Cancer Patients? A Systematic Review of Public Views on Cancer and its Characteristics. PharmacoEconomics, DOI 10.1007/s40273-017-0511-7.

Smith, J. A., Arshad, Z., Thomas, H., Carr, A. J., and Brindley, D. A. (2017). Evidence of insufficient quality of reporting in patent landscapes in the life sciences. Nature Biotechnology, 35, 210-214.

Watkinson, A., Chapman, S., and Horne, R. (2017). Beliefs about pharmaceutical medicines and natural remedies predict variation in placebo analgesia. The Journal of Pain. Doi: 10.1016/j.jpain.2017.02.435. Available here.

Arshad, Z., Karmen, L., Choudhary, R., Smith, J., Branford, O., Brindley, D., Pettitt, D., and Davies, B. (2016). Cell assisted lipotransfer in breast augmentation and reconstruction: A systematic review of safety, efficacy, use of patient reported outcomes and study quality. JPRAS Open, 10, 5–20.

Arshad, Z., Smith, J., Roberts, M., Lee, W., Davies, B., Bure, K., Hollander, G., Dopson, S., Bountra, C., and Brindley, D. (2016). Open Access Could Transform Drug Discovery: A Case Study of JQ1. Expert Opinion On Drug Discovery, 11, 321–332.

Barker, R. (2016). Precision Medicine: What’s All The Fuss About? Scandinavian Journal of Clinical and Laboratory Investigation, 76(S245), 2-5.

Bartley, H., Fasse, K., Horne, R. and Petrie, K.J. (2016). You can’t always get what you want: The influence of choice on nocebo and placebo responding. Annals of Behavioural Medicine, 50(3), 445-451. DOI:10.1007/s12160-016- 9772-1. Available here.

Bidad, N., MacDonald, L., Winters, Z.E., Edwards, S.J.L., Emson, M., Griffin, C.L., Bliss, J. and Horne, R. (2016). How informed is declared altruism in clinical trials? A qualitative interview study of patient decision-making about the QUEST trials (Quality of Life after Mastectomy and Breast Reconstruction). Trials, 17, 431. DOI: 10.1186/s13063-016- 1550-7. 

Bure, K., Ball, A., Biagioni, K., Mehta, S., Choudhary, R., Arshad, Z., Pettitt, D., Holländer, G., Al-Mossawi, H., Faulstich, F., Reeve, B., Smith, J., and Brindley, D. (2016). Automation of CAR-T Cell Adoptive Immunotherapy Bioprocessing: Technology Opportunities to Debottleneck Manufacturing. Bioprocess International, 14. Available here.

Chapman, S., Dale, P., Svedsater, H.,  Stynes, G.,  Vyas, N., Price, D., and Horne, R. (2016) Adherence to asthma medication and preferences for once-daily treatment: Importance of treatment intrusiveness and patient beliefs. European Respiratory Journal, 48, 5018. DOI: 10.1183/13993003.congress-2016.PA5018. Available here.

Churchill, D., Waters, L., Ahmed, N, Angus, B., Boffito, M., Bower, M., Dunn, D., Edwards, S., Emerson, C., Fidler, S., Fisher, M., Horne, R., Khoo, S., Leen, C., Mackie, N., Marshall, N., Monteiro, F., Nelson, M., Orkin, C., Palfreeman, A., Pett, S., Phillips, A., Post F., Pozniak, A., Reeves, I., Sabin, C., Trevelion, R., Walsh, J., Wilkins, E., Williams, I. and Winston, A. (2016). British HIV Association guidelines for the treatment of HIV-1- positive adults with antiretroviral therapy 2015. HIV Medicine, 17(4),  s2-s104. DOI: 10.1111/hiv.12426

Cinar, M., Cinar, F.I., Acikel, C., Yilmaz, S., Çakar, M., Horne, R. and Simsek, I. (2016). Reliability and validity of the Turkish translation of the beliefs about medicines questionnaire (BMQ-T) in patients with Behcet’s disease. Annals of the Rheumatic Diseases The Eular Journal, 75, Suppl 2, 1096. DOI:10.1136/annrheumdis-2016- eular.4884

Clark, E.M., Gould, V.C., Tobias, J.H. and Horne, R. (2016). Natural history, reasons for, and impact of low/non adherence to medications for osteoporosis in a cohort of community-dwelling older women already established on medication: A 2-year follow-up study. Osteoporosis International, 27(2), 579-590. DOI: 10.1007/s00198-015- 3271-2. Available here.

Driesenaar, J.A., De Smet, P.A., van Hulten, R., Horne, R, Zwikker, HE, van den Bemt, B.J. and van Dulmen, S. (2016). Beliefs about inhaled corticosteroids: Comparison of community pharmacists, pharmacy technicians and patients with asthma. Journal of Asthma, 53(10), 1051-1058. DOI:10.1080/02770903.2016.1180696. Available here.

Faulkner, S. D., Lee, M., Qin, D., Morrell, L., Xoxi, E., Sammarco, A., Cammarata, S., Russo, P., Pani, L., and Barker, R. (2016). Pricing and Reimbursement Experiences and Insights in the European Union and the United States: Lessons Learned to Approach Adaptive Payer Pathways. Clinical Pharmacology and Therapeutics, 100(6), 730-742.

Gupta, P., Patel, P., Horne, R., Buchanan, H., Williams, B., and Tomaszewski, M. (2016). How to screen for non- adherence to antihypertensive therapy. Current Hypertension Reports, 18, 89. DOI 10.1007/s11906-016- 0697-7

Luo, D., Smith, J., Meadows, N., Schuh, A., Manescu, K., Bure, K., Davies, B., Horne, R., Kope, M., DiGiusto, D., and Brindley, D. (2016). A Quantitative Assessment of Factors Affecting the Technological Development and Adoption of Companion Diagnostics. Frontiers in Genetics, 357.

MacDonald, L., Chapman, S., Syrett, M., Bowskill, R. and Horne, R. (2016). Improving medication adherence in bipolar disorder: A systematic review and meta-analysis of 30 years of intervention trials. Journal of Affective Disorders, 194, 202-221. DOI:10.1016/j.jad.2016.01.002. Available here.

Meier, A., Faulkner, S. D., Schoonderbeek, C., Jong, B., Kung, J., Brindley, D. and Barker, R. (2016). An Assessment of Implications of Adaptive Licensing for Pharmaceutical Intellectual Property and Regulatory Exclusivity Rights in the European Union. Clinical Pharmacology and Therapeutics, 100(6), 743-753.

Merks, P., Swieczkowski, D., Byliniak, M., Drozd, M., Krupa, K., Jaguszewski, M., Brindley, D., and Naughton, B. (2016). The European Falsified Medicines Directive in Poland: Background, Implementation and Potential Recommendations For Pharmacists. European Journal of Hospital Pharmacy. Available here.

Naughton, B., Smith, J., and Brindley, D. (2016). Establishing Good Authentication Practice (GAP) in Secondary Care to Protect Against Falsified Medicines and Improve Patient Safety. European Journal of Hospital Pharmacy, 23, 118–120.

Naughton, B., Smith, J., Ohanjanyan, A., Smith, G., Dopson, S., Horne, R., and Brindley, D. (2016). EU FMD: hospital pharmacy challenges and opportunities. European Journal of Hospital Pharmacy: Science and Practice. Available here.

Naughton, B., Vadher, B., Smith, J., Smith, G., Chapman, S., Dopson, S., and Brindley, D. (2016). EU Falsified Medicines Directive Mandatory Requirements For Secondary Care: A Concise Review. Journal of Generic Medicines, 12(3), 95–101.

Pearce, C.,  Jochmann, A.,  Bush, A.,  Horne, R. and Fleming, L. (2016). Patterns of nonadherence in children with severe asthma. European Respiratory Journal, 48, 3349. DOI: 10.1183/13993003.congress-2016.PA3349. Available here.

Pettitt, D., Raza, S., Naughton, B., Roscoe, A., Ramakrishnan, A., Ali, A., Davies, B., Dopson, S., Hollander, G., Smith, J., and Brindley, D. (2016). The Limitations of QALY: A Literature Review. Journal of Stem Cell Research and Therapy, 6(4).

Pettitt, D., Smith, J., Fuerstenau-Sharp, M., Bure, K., Holländer, G., Predki, P., Slade, A., Jones, P., Mitrophanous, K., and Brindley, D. (2016). Emerging Platform Bioprocesses For Viral Vectors and Gene Therapies. Bioprocess International, 14. Available here.

Pettitt, D., Smith, J., Meadows, N., Arshad, Z., Schuh, A., DiGiusto, D., Bountra, C., Holländer, G., Barker, R., and Brindley, D. (2016). Regulatory Barriers to the Advancement of Precision Medicine. Expert Review of Precision Medicine Drug Development, 1, 319–329.

Smith, S.G., Sestak, I., Forster, A., Partridge, A., Side, L., Wolf, M.S., Horne, R., Wardle, J. and Cuzick, J. (2016). Factors affecting uptake and adherence to breast cancer chemoprevention: A systematic review and meta-analysis. Annals of Oncology, 27 (4), 575-590.

Smith, S., Side, L., Meisel, S., Horne, R., Cuzick, J., and Wardle, J. (2016). Clinician-reported barriers to implementing breast cancer chemoprevention in the UK: A qualitative investigation. Public Health Genomics, 19(4), 239-249. DOI: 10.1159/000447552

Spiers, J., Smith, J.A., Poliquin, E., Anderson, J. and Horne, R. (2016). The experience of antiretroviral treatment for black West African women who are HIV positive and living in London: An interpretive phenomenological analysis. AIDS and Behaviour. DOI: 10.1007/s10461-015- 1274-9. Available here.

Webber, J., Chapman, S., Carroll, P., McBride, P., Phillips, D., and Horne, R. (2016). Development and evaluation of the acceptability of new materials to address individualised needs to support self-management for patients with adrenal insufficiency. Endocrine Abstracts, 44, 37. Doi :10.1530/endoabs.44.P37

Wileman, V., Chilcot, J., Armitage, C.J., Farrington, K., Wellsted, D.M., Norton, S., Davenport, A., Franklin, G., Da Silva Gane, M., Horne, R. and Almond, M. (2016). Evidence of improved fluid management in patients receiving haemodialysis following a self-affirmation theory-based intervention: A randomised controlled trial. Psychological Health, 31(1), 100-14. DOI: 10.1080/08870446.2015.1073729. Available here.

Archive

2015

Barker, R.W. and Scannell, J.W. (2015) The Life Sciences Translational Challenge: The European Perspective. Therapeutic Innovation & Regulatory Science, 49(3), 415–424. 

Brindley, D., Arshad, Z., Luo, D., Dopson, S., Hollander, G., Frost, S., Bountra, C., and Smith, J. (2015). 21st Century Cures Act: An Act of Cure or Diagnosis? Rejuvenation Research, 18, 295–298.

Brindley, D., Rehki, R., Fuerstenau-Sharp, M., Kantoff, P., Hollander, G., Smith, J., Tindal, S., Timmins, N., and Bure, K. (2015). The Potential Application of Real Time Lot Release Testing in the Biomanufacture of Autologous Cell Based Immunotherapies. Bioprocess International, 13, 1-8. Available here.

Chapman, S.C.E., Barnes, N., Barnes, M., Wilkinson, A., Hartley, J., Piddock, C., Weinman, J. and Horne, R. (2015). Changing adherence-related beliefs about ICS maintenance treatment for asthma: Feasibility study of an intervention delivered by asthma nurse specialists. BMJ Open, 5(6), doi: 10.1136/bmjopen-2014-007354.

Chapman, S., Horne, R., Eade, R., Balestrini, S., Rush, J. and Sisodiya, S. (2015). Applying a perceptions and practicalities approach to understanding nonadherence to anti-epileptic drugs (AEDs). Epilepsia, 56(9), 1398-1407. DOI: 10.1111/epi.13097

Chapman, S.C., LLahana, S., Carroll, P. and Horne, R. (2015). Glucocorticoid therapy for adrenal insufficiency: Nonadherence, concerns and dissatisfaction with information. Clinical Endocrinology, 84(5), 664-71. DOI:10.1111/cen.12991.

Cooper, V., Metcalf, L., Versnel, J., Upton, J., Walker, S., and Horne, R. (2015). Patient-reported side effects, concerns and adherence to corticosteroid treatment for asthma, and comparison with physician estimates of side-effect prevalence: A UK-wide, cross sectional study. Primary Care Respiratory Medicine, 25, 15026. DOI:10.1038/npjpcrm.2015.26.

Eichler, H. G., Baird, L. G., Barker, R., Bloechl-Daum, B., Borlum-Kristensen, F., Brown, J., Chua, R., Del Signore, S., Dugan, U., Ferguson, J., Garner, S., Goettsch, W., Haigh, J., Honig, P., Hoos, A., Huckle, P., Kondo, T., Le Cam, Y., Leufkens, H., Lim, R., Longson, C., Lumpkin, M., Maraganore, J., O’Rourke, B., Oye, K., Pezalla, E., Pignatti, F., Raine, J., Rasi, G., Salmonson, T., Samaha, D., Schneeweiss, S., Siviero, P. D., Skinner, M., Teagarden, J. R., Tominaga, T., Trusheim, M. R., Tunis, S., Unger, T. F., Vamvakas, S., and Hirsch, G. (2015). From Adaptive Licensing to Adaptive Pathways: Delivering a flexible life-span approach to bring new drugs to patients. Clinical Pharmacology & Therapeutics, 97(3), 234-246.

Fasse, K., Grey, A., Horne, R. and Petrie, K. (2015). High perceived sensitivity to medicines is associated with higher medical care utilisation, increased symptom reporting and greater information-seeking about medication. Pharmacoepidemiology and Drug Safety, 24(6), 592-99. DOI: 10.1002/pds/3751. Available here.

French, A., Bravery, C., Wall, I., Chandra, A., Archibald, P., Gold, J. D., Artzi, N., Kim, H-W., Carr, A. J., Barker, R. W., Reeve, B., Meissner, A., Wu, J. C., Knowles, J. C., Williams, D., Garcia-Cardena, G., Sipp, D., Rao, M., Oh, S., Loring, J., Bure, K., Stacey, G., Karp, J. M., Snyder, E. Y., and Brindley, D.A. (2015). Enabling Consistency in Pluripotent Stem Cell-Derived Products for R&D and Clinical Applications Through Material Standards. Stem Cells Translational Medicine, 4(3), 217-223.

Goodfellow, N.A., Hawwa, A., Reid, A.J.M., Horne, R., Shields, M.C. and McElnay, J.C. (2015) Adherence to treatment in children and adolescents with cystic fibrosis: A cross-sectional, multi-method study investigating the influence of beliefs about treatment and parental depressive symptoms. BMC Pulmonary Medicine, 15, 43. DOI: 10.1186/s12890-015- 0038-7

Heller, M.K., Chapman, S.C., and Horne, R. (2015). Beliefs about medication predict the misattribution of a common symptom as a medication side effect – Evidence from an analogue online study. Journal of Psychosomatic Research, 79(6), 519-529.

Horne, R., Bell, J. I., Montgomery, J. R., Ravn, M. O., and Tooke, J. E. (2015). A New Social Contract For Medical Innovation. The Lancet, 385(9975), 1153-1154.

Kumar, K., Raza, K., Nightingale, P., Horne, R., Chapman, S., Greenfield, S. and Gill, P. (2015). Determinants of adherence to disease modifying anti-rheumatic drugs in White British and South Asian patients with rheumatoid arthritis: A cross sectional study. BMC Musculoskeletal Disorders, 16, 396.

Lannon, K., Smith, J., Bure, K., and Brindley, D. (2015). Quantitative Risk Assessment of Bioaccumulation Attributable to Extractables and Leachables in Cellular Immunotherapy Biomanufacturing. Bioprocess International. Available here.

Meadows, N. A., Morrison, A., Brindley, D. A., Schuh, A. and Barker, R. W. (2015). An Evaluation of Regulatory and Commercial Barriers to Stratified Medicine Development and Adoption. The Pharmacogenomics Journal, 15(1), 6-12.

Morys, M., Davie, N., Pigott, R., Kann, T., and Barker, R. (2015). Open Innovation In The Life Sciences: A Qualitative Study of Barriers and Enablers.

O’Neill, J. (2015) Securing New Drugs for Future Generations: The Pipeline of Antibiotics. Available here.

Rekhi, R., Smith, J., Arshad, Z., Roberts, M., Bountra, C., Bingham, I., Bure, K., Brindley, D. (2015). Decision-Support Tools for Monoclonal Antibody and Cell Therapy Bioprocessing Current Landscape and Development Opportunities. Bioprocess International. Available here.

Silva, M., Daheron, L., Hurley, H., Bure, K., Barker, R., Carr, A. J., Williams, D., Kim, H-W., French, A., Coffey, P. J., Cooper-White, J. J., Reeve, B., Rao, M., Snyder, E. Y., Ng, K. S., Mead, B. E., Smith, J. A., Karp, J. M., Brindley, D. A.* and Wall, I. (2015). Generating iPSCs: Translating Cell Reprogramming Science Into Scalable and Robust Biomanufacturing Strategies. Cell Stem Cell, 16(1), 13-17.

Smith, H.E., Jones, C.J., Hankins, M., Field, A., Theadom, A., Bowskill, R. and Horne, R. (2015). The effects of expressive writing on lung function, quality of life, medication use, and symptoms in adults with asthma: A randomised control trial. Psychosomatic Medicine, 77(4), 429-437.

Smith, J., Ng, K., Mead, B., Dopson, B., Reeve, B., Edwards, J., Wood, M., Carr, A., Bure, K., Karp, J., and Brindley, D. (2015). Extracellular Vesicles: Commercial Potential As Byproducts of Cell Manufacturing for Research and Therapeutic Use. Bioprocess Interntational, 13. Available here.

Winters, Z.E., Emson, M., Griffin, C., Mills, J., Hopwood, P., Bidad, N., MacDonald, L., Turton, E.P.L., Horne, R., Bliss, J.M. et al. (2015). Learning from the QUEST multicentre feasibility randomisation trials in breast reconstruction after mastectomy. British Journal of Surgery, 102(1), 45-56. Available here.

2014

Bravery, C. A., and French, A. (2014). Reference Materials For Cellular Therapeutics. Cytotherapy, 16(9), 1187-1196.

Brindley, D., French, A., Baptista, R., Timmins, N., Adams, T., Wall, I., and Bure, K. (2014). Cell Therapy Bioprocessing Technologies and Indicators of Technological Convergence: A Concise Review. BioProcess International, 12(3), Available here.

Chapman, S.C.E., Horne, R., Chater, A., Hukins, D. and Smithson, W.H. (2014). Patients’ perspectives on antiepileptic medication: Relationships between beliefs about medicines and adherence among patients with epilepsy in UK primary care. Epilepsy and Behavior, 31, 312-320.

Chater, A.C., Parham, R., Riley, S., Hutchison, A.J. and Horne, R. (2014). Profiling patient attitudes to phosphate binding medication: A route to personalising treatment and adherence support. Psychology and Health, 29(12), 1407-1420. Available here.

Davies, B. M., Rikabi, S. R., French, A., Pinedo-Villanueva, R., Morrey, M. E., Wartolowska, K., Judge, A., MacLaren, R.E., Mathur, A., Williams, D. J., Wall, I., Birchall, M., Reeve, B., Atala, A., Barker, R. W., Cui, Z., Furniss, D., Bure, K., Snyder, E. Y., Karp, J. M., Price, A., Carr, A., and Brindley, D.A. (2014). Qualitative Assessment of Barriers to the Clinical Development and Adoption of Cellular Therapies: A Pilot Study. Journal of Tissue Engineering, 5, 1-8.

Dorling, A., Rebollo-Mesa, I., Hilton, R., Peacock, J.L., Vaughan, R., Gardner, L. Danzi, G., Baker, R., Clark, B., Thuraisingham, R.C., Buckland, M., Picton, M., Martin, S., Borrows, R., Briggs, D., Horne, R., McCrone, P, Kelly, J. and Murphy, C. (2014). Can a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: Study protocol for the multicentre randomised controlled OuTSMART trial. Trials, 15, 30.

Fall, E., Gauchet, A., Izaute, M., Horne, R. and Chakroun, N. (2014). Validation of the French version of the Beliefs about Medicines Questionnaire (BMQ) among diabetes and HIV patients. Revue européenne de psychologie appliquée, 64, 335-343.

Fouque, D., Horne, R., Cozzolino, M. and Kalantar-Zadeh, K. (2014). Balancing nutrition and serum phosphorus in maintenance dialysis. AJKD in Practice, 64(1), 143-150. Available here.

French, A., Bure, K. and Brindley D.A. (2014). An Assessment of the Key Barriers to the Commercialization and Clinical Adoption of Pluripotent Stem Cell Therapies. Rejuvenation Research, 17(1), DOI: 10.1089/rej.2014.1545.

French, A., Suh, J. Y., Suh, C. Y., Rubin, L., Barker, R., Bure, K., Reeve, B., and Brindley, D, A. (2014). Global Strategic Partnerships in Regenerative Medicine. Trends in Biotechnology, 32(9), 436–440.

Geddes J., Cipriani, A., and Horne, R. (2014). Communicating the harmful effects of medicines. BMJ, 348. DOI: 10.1136/bmj.g4047. Available here.

Kendler, D.L., Macarios, D., Lillestol, M.J., Moffett, A., Satram-Hoang, S., Huang, J., Kaur, P., Tang, E-T., Wagman, R. and Horne, R. (2014). Influence of patient perceptions and preferences for osteoporosis medication on adherence behaviour in the Denosumab Adherence Preference Satisfaction study. Menopause, 21(1), 25-32. Available here.

Linn, A.J., van Weert, J.C. van Dijk, L., Horne, R. and Smith, E.G. (2014). The value of nurses’ tailored communication when discussing medicines: Exploring the relationship between satisfaction, beliefs and adherence. Journal of Health Psychology, 21(5), 798-807. DOI: 10.1177/1359105314539529

O’Neil, A., Williams, E.D., Browne, J.L., Horne, R., Pouwer, F. and Speight, J. (2014). Associations between economic hardship and markers of self-management in adults with type 2 diabetes: Results from Diabetes MILES – Australia. Australian and New Zealand Journal of Public Health, 38(5), 466-472.

Purves, J. (2014). Regulation- Innovation Interactions and the Development of Antimicrobial Drugs:  An Evaluation of Drugs and IVD Regulation. Available here.

Roberts, M., Wall, I. B., Bingham, I., Icely, D., Reeve, B., Bure, K., French, A., Brindley, D.A. (2014). The Global Intellectual Property Landscape of Induced Pluripotent Stem Cell Technologies. Nature Biotechnology, 32, 742-748.

Scannell, J. (2014). Regulation-Innovation Interactions and the Development of Antimicrobial Drugs and Diagnostics for Human and Animal Diseases: An Evaluation of Drug and IVD Industry Views. Available here.

Scannell, J. and Bruce, A. (2014). Regulation-Innovation Interactions and the Development of Veterinary Antimicrobial Drugs and Diagnostic. Available here.

Schoeler, N.E., Sander, J.W., Sisodiya, S.M., Cross, H.J., MacDonald, L., Horne, R., Champion, H. (2014). Assessing parents’ attitudes towards ketogenic dietary therapies. Epilepsy and Behaviour, 39, 1-5. Available here.

Smith, G., Smith, J., and Brindley, D. (2014). The Falsified Medicines Directive: How to Secure Your Supply Chain. Journal of Generic Medicines, 11, 169–172.

Stack, R.J., Mallen, C.D., Deighton, C., Kiely, P., Shaw, K.L., Booth, A., Kumar, K., Thomas, S., Rowan, I., Horne, R., Nightingale, P., Herron-Marx, S., Jinks, C. and Raza, K. (2014). The development and initial validation of a questionnaire to measure help-seeking behaviour in patients with new onset rheumatoid arthritis. Health Expectations, 18(6), 2340-2355. DOI: 10.1111/hex.12203.

Tait, J., Bruce, A., Mittra, J., Purves, J., and Scannell, J. (2014). Regulation-Innovation Interactions and the Development of Antimicrobial Drugs and Diagnostics for Human and Animal Diseases. Available here.

Uguen, D., Lönngren, T., Le Cam, Y., Garner, S., Voisin, E., Incerti, C., Dunoyer, M., and Slaoui, M. (2014). Accelerating Development, Registration and Access to Medicines For Rare Diseases in the European Union Through Adaptive Approaches: Features and Perspectives. Orphanet Journal of Rare Diseases, 9 (20), doi: 10.1186/1750-1172-9-20.

Wartolowska, K., Judge, A., Hopewell, S., Collins, G. S., Dean, B. J. F., Rombach, I., Brindley, D., Savulescu, J., Beard, D. J., and Carr, A. J. (2014). Use of Placebo Controls in the Evaluation of Surgery: Systematic Review. BMJ, 348, doi: http://dx.doi.org/10.1136/bmj.g3253.

Winters, Z.E., Griffin, C., Horne, R., Bidad, N and McCulloch, P. (2014). Barriers to accrue to clinical trials and possible solutions. British Journal of Cancer, 111, 637-639, DOI: 10.1038/bjc.2014.318.

2013

Barker, R., Brindley, D. and Schuh, A. (2013) Establish Good Genomic Practice to Guide Medicine Forward. Nature Medicine, 19(5), 530.

Brindley, D., Barker, R. and Lachmann, P. (2013). Health Care: Better Drug Access For Terminal Patients. Nature, 502(7469), 38.

Brindley, D. A., French, A., Suh, J., Roberts, M., Davies, B., Pinedo-Villanueva, R., Wartolowska, K., Rooke, K., Kramm, A., Judge, A., Morrey, M., Chandra, A., Hurley, H., Grover, L., Bingham, I., Siegel, B., Rattley, M. S., Buckler, R. L., McKeon, D., Krumholz, K., Hook, L., May, M., Rikabi, S., Pigott, R., Morys, M., Sabokbar, A., Titus, E., Laabi, Y., Lemaitre, G., Zahkia, R., Sipp, D., Horne, R., Bravery, C., Williams, D., Wall, I., Snyder, E. Y., Karp, J. M., Barker, R. W., Bure, K., Carr, A. J., and Reeve, B. (2013). The Implementation of Novel Collaborative Structures For The Identification and Resolution of Barriers to Pluripotent Stem Cell Translation. Stem Cells and Development, 22(S1), 63-72. 

Brindley, D. A, Wall, I. B. and Bure, K. (2013). Automation of Cell Therapy Biomanufacturing: Minimizing Regulatory Risks and Maximising Return on Investment. Bioprocess International, Supplement, 11(S3), 18–25.

Forda, S., Bergström, R., Chlebus, M., Barker, R., and Høngaard Andersen, P. (2013). Priorities For Improving Drug Research, Development and Regulation. Nature Reviews Drug Discovery, 12, 247-248.

French, A., Buckler, R. L. and Brindley, D. A. (2013). Commercialization of Regenerative Medicine: Learning From Spin-Outs. Rejuvenation Research, 16(2), 164-70.

Green, D.W., Horne, R. and Shephard, E.A. (2013). Public perceptions of the risks, benefits and use of natural remedies, pharmaceutical medicines and personalised medicines. Complementary Therapies in Medicine, 21(5), 487-491. Available here.

Guillemin, F., Martinez, L., Calvert, M., Cooper, C., Ganiats, T.G., Gitlin, M., Horne, R., Marciniak, A., Pfeilschifter, J., Shepherd, S., Tosteson, A.N.A., Wade, S., Macarios, D. and Freemantle N. (2013). Fear of falling, fracture history and comorbidities are associated with health-related quality of life among European and US women with osteoporosis in a large international study. Osteoporosis International, 1-10.

Haverkamp, F., Norgren, S., Horne R. and Gasteyger, C. (2013). The role of electronic assessment of adherence in the education and counselling of children taking growth hormone: Progress and challenges. Paediatric Endocrinology Reviews, 10(2), 199-208. Available here.

Horne, R., Chapman, S.C.E., Forbes, A., Parham, R., Freemantle, N. and Cooper, V. (2013). Understanding patients’ adherence-related beliefs about prescribed medicines: A meta-analytic review of the Necessity-Concerns Framework. PLoSONE, 8(12) e80633. DOI:10.1371/journal.pone.0080633. 

Horne, R., Fasse, K., Cooper, V., Diefenbach, M.A., Leventhal, H., Leventhal, E. and Petrie, K. (2013). The Perceived Sensitivity to Medicines (PSM) Scale: An evaluation of validity and reliability. British Journal of Health Psychology, 18(1), 18-30. Available here.

Karamanidou, C., Weinman, J., and Horne, R. (2013). A qualitative study of treatment burden among haemodialysis recipients. Journal of Health Psychology, 19(4), 556-569. Available here.

Kumar, K., Raza, K., Nightingale, P., Horne, R., Shaw, K., Greenfield, S. and Gill, P. (2013). A mixed methods protocol to investigate medication adherence in patients with rheumatoid arthritis in patients with rheumatoid arthritis of White British and South Asian origin. BMJ Open, 3: e001836. DOI:10. 1136/bmjopen-2012- 001836.

Matoulkova, P., Krulichova, I.S., Macek, K., Vlcek, J., Bastecka, D., Prixova, M. and Horne, R. (2013). Chronically ill Czech patients’ beliefs and medicines: The psychometric properties and factor structure of the BMQ-CZ. Therapeutic Innovation and Regulatory Science, 47(3), 341-348. Available here.

Salgado, T., Marques, A., Geraldes, L., Benrimoj, S., Horne, R. and Fernandez- Llimos F. (2013). Cross-cultural adaptation of the Beliefs about Medicines Questionnaire into Portuguese. Sao Paulo Medical Journal, 13(2),88-94.

2012

Barker, R. and Garner, S. (2012). Adaptive drug development and licensing. Regulatory Rapporteur, 9(10), 13-14.

Brindley, D., Davie, N., Sahlman, W., Bonfiglio, G., Culme-Seymour, E., Reeve, B., Mason, C. (2012). Promising Growth and Investment in the Cell Therapy Industry During the First Quarter of 2012. Cell Stem Cell, 10, 492–496.

Brindley, D., Davie, N.., Culme-Seymour, E., and Mason, C. (2012). Streamlining Cell Therapy Manufacturing: From Clinical to Commercial Scale. Bioprocess International, 10, 24-29. Available here.

Brindley, D., and Mason, C. (2012). News Commentary: Human Embryonic Stem Cell Therapy in the Post-Geron Era. Regenerative Medicine, 7, 17–18.

Brindley, D., Reeve, B., and Mason, C. (2012). Pharmaceutical Industry: Investors Unfazed by Drug-Patent Expiry. Nature, 481 (7381), 265.

Cooke, J., Bowskill, R., Clatworthy, J., LeSeve, P., Rank, T., Parham, R. and Horne, R. (2012). Health professionals’ beliefs about medication for bipolar disorder. The Journal of Mental Health Training, Education and Practice, 7(1), 4-8. Available here.

Culme-Seymour, E., Davie, N., Brindley, D., Edwards-Parton, S., and Mason, C. (2012). A Decade of Cell Therapy Clinical Trials (2000-2010). Regenerative Medicine, 7, 455–462.

Mahler, C., Hermann, K., Horne, R., Jank, S., Haefeli, W.E. and Szecsenyi, J. (2012). Patients beliefs about medicines in a primary care setting in Germany. Journal of Evaluation in Clinical Practice, 18(2), 409-413. Available here.

Salt, E., Hall, L., Peden, A.R. and Horne, R. (2012) Psychometric properties of three medication adherence scales in patients with rheumatoid arthritis. Journal of Nursing Measurement, 20(1), 59-72. Available here.

Trachtenberg, F.L., Mednick, L., Kwiatkowski, J.L., Neufeld, E., Haines, D., Pakbaz, Z., Thompson, A.A., Quinn, C.T., Grady, R., Sobota, A., Olivieri, N., Horne, R. and Yamashita, R. (2012). Beliefs about chelation among thalassemia patients. Health and Quality of Life Outcomes, 10(1), 148.

2011

Abdel-Tawab, R., James, D.H., Fichtinger, A., Clatworthy, J., Horne, R. and Davies, G. (2011). Development and validation of the Medication-Related Consultation Framework (MRCF). Patient Education and Counselling, 83(3), 451-7. Available here.

Brindley, D., Davie, N., Culme-Seymour, E., Mason, C., Smith, D., and Rowley, J. (2011). Peak Serum: Implications of Serum Supply For Cell Therapy Manufacturing. Regenerative Medicine, 7, 7–13.

Brindley, D., Moorthy, K., Lee, J-H., Mason, C., Kim, H-W., Wall, I. (2011). Bioprocess Forces and Their Impact on Cell Behavior: Implications for Bone Regeneration Therapy. Journal of Tissue Engineering, 2.

Brindley, D., Reeve, B., Sahlman, W., Bonfiglio, G., Davie, N., Culme-Seymour, E., and Mason, C. (2011). The Impact of Market Volatility on the Cell Therapy Industry. Cell Stem Cell, 9, 397–401.

Cooper, V., Moyle G.J., Fisher, M., Reilly, G., Ewan, J., Liu, H.C. and Horne, R. (2011). Beliefs about antiretroviral therapy, treatment adherence and quality of life in a 48-week randomised study of continuation of zidovudine/lamivudine or switch to tenofovir DF/emtricitabine, each with efavirenz. AIDS Care, 23(6), 705-13. Available here.

Denyer, K., Smith, H., Davies, K., Horne, R., Hankins, M. and Walker-Bone, K. (2011). A pilot study to compare the views of traditionally trained and CAM-trained therapists using the clinical exemplar of management of neck/upper limb pain to assess barriers to effective integration of approaches. Complementary Therapies in Medicine, 20(1-2), 38-44. Available here.

Gold, D.T, Horne, R., Coon, C.D., Price, M.A., Borenstein, J., Varon, S.F., Satram-Hoang, S. and Macarios, D. (2011). Development, reliability, and validity of a new preference and satisfaction questionnaire. Value in Health, 14(8), 1109-16. Available here.

Kumar, K., Gordon, C., Barry, R., Shaw, K., Horne, R. and Raza, K. (2011). ‘It’s like taking poison to kill poison but I have to get better’: A qualitative study of beliefs about medicines in RA and SLE patients of South Asian origin. Lupus, 20(8), 837-44. Available here.

Mason, C., Brindley, D., Culme-Seymour, E., and Davie, N. (2011). Cell Therapy Industry: Billion Dollar Global Business With Unlimited Potential. Regenerative Medicine, 6, 265–272.

Mora, P.A., Berkowitz, A., Contrada, R.J., Wisnivesky, J., Horne, R., Leventhal, H. and Halm, E.A. (2011). Factor structure and longitudinal invariance of the Medical Adherence Report Scale-Asthma. Psychology and Health, 26(6), 1-15. Available here.

Stack, R., Shaw, K., Mallen, C., Herron-Marx, S., Horne, R. and Raza, K. (2011). Delays in help seeking at the onset of the symptoms of rheumatoid arthritis: a systematic synthesis of qualitative literature. Annals of the Rheumatic Diseases, 71(4), 493-497. Available here.

Willmott, L., Harris, P., Gellaitry, G, Cooper, V. and Horne, R. (2011). The effects of expressive writing following first myocardial infarction: A randomised control trial. Health Psychology, 30(5), 642-50. Available here.

2010

Argentero, P., Torchio, E., Tibaldi, G., Horne, R., Clatworthy, J. and Munizza, C. (2010). The beliefs about drug treatment. The Italian version of the BMQ (the Beliefs about Medicines Questionnaire): Its validity and applicability. Epidemiologia e Psichiatria Sociale, 19(1), 86-92.

Cooper, V., Horne, R. and Ewan, J. (2010). Switching to Atripla (EFV/FTC/TDF) from Kivexa (ABC/3TC) plus EFV leads to improved perceptions of treatment: results from the ROCKET 1 study. Journal of the International AIDS Society, 13(4), 42.

Cooper, V., Horne, R., Gellaitry, G., Vrijens, B., Lange, A.C., Fisher, M. and White, D. (2010). The impact of once-nightly versus twice-daily dosing and baseline beliefs about HAART on adherence to efavirenz-based HAART over 48 weeks: The NOCTE study. Journal of Acquired Immune Deficiency Syndromes, 53(3), 369-77. Available here.

Freemantle, N., Cooper, C., Roux, C., Díez-Pérez, A., Guillemin, F., Jonsson, B., Ortolani, S., Pfeilschifter, J., Horne, R., Kakad, S., Shepherd, S. Möller, G., Marciniak, A. and Martinez, L. (2010). Baseline observations from the POSSIBLE EU® study: Characteristics of postmenopausal women receiving bone loss medications. Archives of Osteoporosis, 5(1-2), 61-72.

Gellaitry, G., Peters, K., Bloomfield, D. and Horne, R. (2010). Narrowing the Gap: The effects of an expressive writing intervention on perceptions of actual and ideal emotional support in women who have completed treatment for early stage breast cancer. Psycho-Oncology, 19(1), 77-84. Available here.

Horne, R., Clatworthy, J. and Hankin, M., on behalf of the ASCOT Investigators (2010). High adherence and concordance within a clinical trial of antihypertensives. Chronic Illness, 6(4), 243-251. Available here.

Jackson, C.A., Clatworthy, J., Robinson, A. and Horne, R. (2010). Factors associated with non-adherence to oral medication for inflammatory bowel disease: A systematic review. The American Journal of Gastroenterology, 105(3), 525-39. Available here.

Kendler, D.L., Bessette, L., Hill, C.D., Gold, D.T., Horne, R., Varon, S.F., Borenstein, J., Wang H., Man, H.S., Wagman, R. B., Siddhanti, S., Macarios, D. and Bone, H. G. (2010). Preference and satisfaction with a 6-month subcutaneous injection versus a weekly tablet for treatment of low bone mass. Osteoporosis International, 21(5), 837-846. Available here.

Mahler, C., Hermann, K., Horne, R., Ludt, S., Haefeli, W.E., Szecsenyi, J. and Jank, S. (2010). Assessing reported adherence to pharmacological treatment recommendations. Translation and evaluation of the Medication Adherence Report Scale (MARS) in Germany. Journal of Evaluation in Clinical Practice, 16(3), 574-579. Available here.

Nestoriuc, Y., Orav, E.J., Liang, M.H., Horne, R. and Barsky, A.J. (2010). Prediction of nonspecific side effects in rheumatoid arthritis patients by beliefs about medicines. Arthritis Care and Research, 62(6), 791-9.

Price, D., Robertson, A., Bullen, K., Rand, C., Horne, R. and Staudinger, H. (2010). Improved adherence with once-daily versus twice-daily dosing of mometasone furoate administered via a dry powder inhaler: A randomized open-label study. BMC Pulmonary Medicine, 10(1).

2009

Brindley, D., and Davie, N. (2009). Regenerative Medicine Through a Crisis: Social Perception and the Financial Reality. Rejuvenation Research, 12, 455–461.

Bucks, R.S., Hawkins, K., Skinner, T.C., Horn, S., Seddon, P. and Horne, R. (2009). Adherence to treatment in adolescents with cystic fibrosis: The role of illness perceptions and treatment beliefs. Journal of Pediatric Psychology, 34(8), 893-902.

Clatworthy, J., Bowskill, R., Parham, R., Rank, T. Scott, J. and Horne, R. (2009). Understanding medication non-adherence in bipolar disorders using a Necessity-Concerns Framework. Journal of Affective Disorders, 116(1-2), 51-55. Available here.

Clatworthy, J., Price, D., Ryan, D., Haughney, J., and Horne, R. (2009). The value of self-report assessment of adherence, rhinitis and smoking in relation to asthma control. Primary Care Respiratory Journal, 18(4), 300-305. Available here.

Cohen, J.L., Mann, D.M, Wisnivesky, J.P., Leventhal, H., Horne, R., Musumeci-Szabó, T.J. and Halm, E.A. (2009). Assessing the validity of self-reported medication adherence among inner-city asthmatic adults: The Medication Adherence Reporting Scale for Asthma. Annals of Allergy, Asthma and Immunology, 103(4), 325-31. Available here.

Cooper, V., Gellaitry, G., Hankins, M., Fisher, M. and Horne, R. (2009). The influence of symptom experiences and attributions on adherence to Highly Active Anti-Retroviral Therapy (HAART): a six month prospective, follow-up study. AIDS Care, 21(4), 520-528. Available here.

Figueiras M. J., Alves, N., Marcelino, D. A., Cortes, M., Weinman. J., and Horne, R. (2009). Assessing lay beliefs about generic medicines: Development of the generic medicines scale. Psychology, Health and Medicine, 14(3), 311-21. Available here.

Horne, R., Kovacs, C., Katlama, C., Clotet, B., Fumaz, C. R., Youle, M., Kulasegaram, R., Fisher, M., Cohen, C., Slim, J., Shalit, P., Cooper, V. and Tsoukas, C. (2009). Prescribing and using self-injectable antiretrovirals: How concordant are physician and patient perspectives? AIDS Research and Therapy, 6(2), 300-305.

Horne, R., Parham, R., Driscoll, R. and Robinson, A. (2009). Patients’ attitudes to medicines and adherence to maintenance treatment in Inflammatory Bowel Disease (IBD). Inflammatory Bowel Diseases, 15(6), 837-44. Available here.

Mahler, M., Jank, S., Hermann, K., Horne, R., Ludt, S., Haefeli, W.E. and Szecsenyi, J. (2009). Psychometric properties of a German version of the Satisfaction with Information about Medicines Scale (SIMS-D). Value in Health, 12(8), 1176-1179. Available here.

Moshkovska, T., Stone, M. A., Clatworthy, J., Smith, R. M., Bankart, J., Baker, R., Wang, J., Horne, R. and Mayberry, J. F. (2009). An investigation of medication adherence to 5-aminosalicylic acid therapy in patients with ulcerative colitis, using self-report and urinary drug excretion measurements. Alimentary Pharmacology and Therapeutics, 30(11-12), 1118-1127. Available here.

Parham, R., Riley, S., Hutchinson, A. and Horne, R. (2009). Renal dialysis patients’ satisfaction with information about Phosphate-Binding Medication. Journal of Renal Care, 35(s1), 86-93. Available here.

Tibaldi, G., Clatworthy, J., Torchio, E., Argentero, P., Munizza, C. and Horne, R. (2009). The utility of the Necessity-Concerns Framework in explaining treatment non-adherence in four chronic illness groups in Italy. Chronic Illness, 5(2), 129-33. Available here.

Book Chapters

Halioua-Haubold, C., Arshad, Z., Brindley, D., and Smith, J. (in press). Regulatory Considerations for Cell- Based Medicinal Products. In Regulatory Affairs Professionals Society, eds., Fundamentals of EU Regulatory Affairs, 8th ed., Regulatory Affairs Professionals Society Publishing.

Naughton, B., Koshkouei, M., Smith, J., Brindley, D., and Jacob, C. (in press). International Counterfeit Medicine Regulation. In Regulatory Affairs Professionals Society, eds., Fundamentals of EU Regulatory Affairs, 8th ed., Regulatory Affairs Professionals Society Publishing.

Ware, J., Brindley, D., and Smith, J. (in press). Products Manufactured From Human Blood and Plasma. In Regulatory Affairs Professionals Society, eds., Fundamentals of EU Regulatory Affairs, 8th ed., Regulatory Affairs Professionals Society Publishing.

Ware, J., Brindley, D., and Smith, J. (in press). Products Manufactured From Human Blood and Plasma. In Regulatory Affairs Professionals Society, eds., Fundamentals of EU Regulatory Affairs, 8th ed., Regulatory Affairs Professionals Society Publishing.

Smith, J., Dopson, S., Davies, B., Wartolowska, K., Karp, J., Carr, A., and Brindley, D. (2016). Borderline Regulation of Stem Cell Technologies: Therapies, Devices and Combination Products. In Regulatory Affairs Professionals Society, eds., Global Medical Device Regulatory Strategy. Regulatory Affairs Professionals Society Publishing.

Smith, J., French, A., Hurley, H., Davies, B., Dopson, S., Fairchild, P., Roberts, M., Riley, P., Reeve, B., Williams, D., Daheron, L., Bure, K., Carr, A., Karp, J., Wall, I., and Brindley, D. (2016). Challenges and Opportunities in the Development of Induced Pluripotent Stem Cell Therapeutics. In S. A. and Atta-ur-Rahman, eds., Frontiers of Stem Cell and Regenerative Medicine, Volume 2, Bentham Science.

Archive

2015

Smith, J., Bravery, C., Hollander, G., and Brindley, D. (2015). Regulating Regenerative Medicine: Cell Therapy, Gene Therapy and Tissue Engineering. In Regulatory Affairs Professionals Society, eds., Fundamentals of EU Regulatory Affairs, 7th ed. Regulatory Affairs Professionals Society Publishing.

Smith, J., Naughton, B., Kramm, A., Smith, G., Ohanjanyan, A., De Simone, M., Horne, R., and Brindley, D. (2015). European Union Falsified Medicines Directive: Requirements and Implications for Multi-Stakeholder Healthcare Delivery. In Regulatory Affairs Professionals Society, eds., Fundamentals of EU Regulatory Affairs, 7th ed. Regulatory Affairs Professionals Society Publishing.

Smith, J., Reeve, B., Carr, A., and Brindley, D. (2015). Regulating Regenerative Medicine: Cell Therapy, Gene Therapy and Tissue Engineering.  In Regulatory Affairs Professionals Society, eds., Fundamentals of US Regulatory Affairs, 9th ed. Regulatory Affairs Professionals Society Publishing.

2013

Brindley, D., Smith, D., Davie, L., and Carmen, J. (2013). Cell Therapy Manufacturing: Identifying and Meeting Demand. In A. Vertes, ed., The Commercial Translation of Cell Based Therapies. Springer.

Brindley, D.A. & Wall, I.B. (2013). The Commercial Manufacture of Cell Therapies. In V. Salih, ed., Standardization in Cell and Tissue Engineering: Methods and Protocols, 1st ed, Cambridge: Woodhead Publishing, 212-239.

2012

Brindley, D., and Mason, C. (2012). Cell Therapy Commercialization. In A. Atala, ed., Progenitor and Stem Cell Technologies and Therapies, 1st ed., Woodhead Publishing.

Policy Papers

Centre for the Advancement of Sustainable Medical Innovation (CASMI) (2016). Medicines Adaptive Pathways for Patients (MAPPS). [online] Oxford: Centre for the Advancement of Sustainable Medical Innovation (CASMI). Available here.

Barker, R., Pigott, R. and Stokes, K. (2014). Which doctors take up promising ideas? New insights from open data. [online] London: Nesta. Available here.

Cline, H., Ranson, P., Garner, S. and Hill, C. (2014). Connectivity, Adaptive Pathways & Deal Structuring. Business Development & Licensing Journal, 21, 24-29.

Pigott. R., Barker, R., Kaan, T., and Roberts, M. (2014). Shaping the Future of Open Innovation: A Practical Guide For Life Sciences Organisations. The Wellcome Trust.

The Academy of Medical Sciences (2013). Realising the Potential of Stratified Medicine. [online] London: Academy of Medical Sciences. Available here.